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Showing posts with label Surgery. Show all posts
Showing posts with label Surgery. Show all posts

Saturday, July 4, 2009

Cancer Research: New surgery seen to have potential in cervical cancer

Studies have postulated that a new form of surgery called mesometrial resection (TMMR) (a more targeted surgical operation) could lead to a significant improvement in the survival rate of patients afflicted with cervical cancer. At the same time, the surgery also promised other improvements such as reduced complications, reducing damages to nerves in the pelvis (thus reducing post-surgery problems with bladder and bowel functionality), and also sparing patients of radiotherapy (link to article):


Survival rates among cervical cancer patients may be improved by as much as 20 per cent by making subtle changes to major surgery, researchers in Germany suggest. The new technique removes a specific, more defined, section which includes the fallopian tubes, uterus, and certain parts of the vagina, which the researchers said are the main areas of local tumour spread.
"Based on historical controls, TMMR without adjuvant radiation has the potential to improve survival by 15-20 per cent," the BBC quoted Hockel as saying. He conceded that it was next needed to conduct larger trials in different hospitals. "This new surgical technique seems to have the potential to help women with early-stage cervical cancer avoid some of the unpleasant long-term effects of a hysterectomy and radiotherapy," Liz Woolf, head of Cancer Research UK's patient information website CancerHelp UK, said.


The improved surgery sounds promising, since it not only improves the survival rate of this cancer, but also seems to reduce the post-surgery complications suffered by patients.

Tuesday, May 5, 2009

Cancer research: Personalizing treatment for lung cancer

One of the key areas of cancer research is to find more methods for personalizing cancer research. This article talks about some interesting leads in this area, including the use of cancer vaccines and targeted therapies to help people who have lung cancer, especially those who have had surgery; such treatment can help people avoid a recurrence of the cancer (link to article):


"Personalizing therapy is the key strategy for longer and better survival in lung cancer," said Prof Paris Kosmidis, head of the second Medical Oncology Department at Hygeia Hospital in Athens, Greece. "This is particularly important for early stage disease when following surgery, decisions about preventive therapy are based on specific prognostic and predictive factors."
At the conference, researchers will describe a gene signature that might predict which patients will benefit from the treatment. "Because the benefits of vaccination will be limited to a subgroup of patients, strategies to define these patients by means of biomarkers such as a genetic signature are of major clinical relevance, as only these patients might be candidates for vaccination in the future,” said Weder.


As we proceed on research, science keeps on finding weapons in the fight cancers; and one of the most worrisome issues for a patient who has had the removal of their cancer is whether the cancer will come back - this research points to indicators about how to prevent the delay.

Friday, May 1, 2009

External article: Can weight loss surgery reduce or reverse diabetes

Was searching for the answer to a question about whether having weight loss surgery can actually reduce the level of diabetes, or actually reverse the diabetes altogether. And I found this article (link to article)


Many people who are overweight or morbidly obese have metabolic syndrome (which is also called pre-diabetes) or have frank diabetes, which is also called adult-onset diabetes, type 2 diabetes, or non-insulin dependent diabetes mellitus (which, despite the name, may be treated with insulin). The hallmark of frank diabetes is high circulating levels of insulin and a resistance to that insulin, leading to higher-than-normal blood sugars.
Weight loss, by diet and exercise or by change in diet gastric bypass, very often improves insulin sensitivity and blood sugar control. Indeed, weight loss may eliminate the need for medical treatment of the condition. We in medicine usually still consider these folks diabetics, as they usually still have abnormal response to a high-sugar meal, but their blood sugar patterns are far better than before the weight loss and/or gastric bypass and their risk of diabetes complications is dramatically reduced.


People who are obese or over-weight are suspectible to high levels of diabetes, and it is important that they reduce their weight as soon as possible; further, their is a chance that their levels of blood sugar and diabetes affliction may reduce if their weight levels come down.